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Chem Res Toxicol 14:611650 Jalas J, Hecht SS, Murphy SE (2005) Cytochrome P 450 2A enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen

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And I dont think that anyone who grows tobacco in Winston-Salem or North Carolina or Georgia or other States that produce tobacco would say that the research program in recent years has not been beneficial So, I would say theres a well-balanced campaign to protect the health of our Nation, which is Joe Califanos responsibility, on the one hand, and to preserve the health and stability of the tobacco industry, which is under Bob Berglund, Secretary of Agriculture, and myself